Baseline prostate-specific antigen compared with median prostate-specific antigen for age group as predictor of prostate cancer risk in men younger than 60 years old

Abstract Objectives Limited data are available concerning the extent to which the initial prostate-specific antigen (PSA) measurement in men younger than age 60 predicts for the risk of prostate cancer (CaP) and how this compares to other known risk factors. Methods From 1991 to 2001, 13,943 men younger than 60 years old participated in a CaP screening study. Men aged 40 to 49 years were eligible for the study if they had a positive family history or African-American heritage, and men older than 50 years were screened without respect to risk factors. The CaP detection rate, PSA velocity, pathologic features, …

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The Swinging Pendulum of PSA Screening

Tide of opinion turning again In 2012, the U.S. Preventive Services Task Force (USPSTF) — a powerful, voluntary group that sets guidelines for primary care physicians — came out against the mass screening of healthy men with prostate-specific antigen (PSA) blood tests for the early detection of prostate cancer. That statement, which was somewhat reversed in 2018, has lived on and continues to fuel hot debates over the use of screening and whether the guidelines themselves caused more harm than benefit. And there likely will be more arguments in the years ahead as medical groups conduct uptakes on guidelines and …

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“The Talk” Webinar Video

“The Talk” is not about the birds and the bees; it’s about talking to your sons and daughters about possibly inheriting genes that predispose them to prostate and breast cancer. View video.

A Re-think About PSA Testing

Benefits of PSA Test for Prostate Cancer Substantially Greater than Generally Appreciated The benefits of the prostate-specific antigen (PSA) test to screen men for prostate cancer may be greater than the harm, say investigators at Weill Cornell Medicine, NewYork-Presbyterian, University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center. While organizations such as the U.S. Preventative Services Task Force (USPSTF) and the American Academy of Family Physicians have been lukewarm or opposed to the routine use of the PSA test, in a commentary published in the New England Journal of Medicine, the investigators demonstrate that these recommendations …

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New test may help detect prostate cancer earlier and with greater accuracy

A new type of test that uses complex sugars to detect prostate cancer earlier and with greater accuracy is being developed by researchers at the University of Birmingham. The test works by identifying sugars, known as glycans, in blood. These sugars are attached to protein molecules called PSA and are known to undergo distinct but subtle changes when cancer is present in the body. Read the article.

Video: “Imaging in Prostate Cancer”

July 2019 Awareness Night Imaging in Prostate Cancer, The Whats, Wheres, Whys and Whens Dr. Chirag Patel,]BSc (Hons), MBBS, MRCP, FRCR Asst Prof., U. of Toronto Dept of Medical Imaging Site Lead, U. of Toronto Abdominal Imaging Fellowship Program Abdominal Radiologist and Head of Abdominal Imaging Division, Sunnybrook Health Sciences Centre, Dept of Medical Imaging   CLICK ON THE ARROW TO START THE VIDEO The Complete Presentation 1:06:02 minutes <  

Video: “Prostate Cancer and the Genes You Are Born With”

September 2019 Awareness Night Prostate Cancer and the Genes You Are Born With Dr. Neil Fleshner, MD, MPH, FRCSC Chair & Professor, University of Toronto Department of Urology Head,Division of Urology University Health Network (incorporating Princess Margaret Cancer Centre)     CLICK ON THE ARROW TO START THE VIDEO The Complete Presentation 39:59 minutes <

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