Baseline prostate-specific antigen compared with median prostate-specific antigen for age group as predictor of prostate cancer risk in men younger than 60 years old

PSA Screening, Diagnosis / By / / 2 minutes of reading

Abstract Objectives Limited data are available concerning the extent to which the initial prostate-specific antigen (PSA) measurement in men younger than age 60 predicts for the risk of prostate cancer (CaP) and how this compares to other known risk factors. Methods From 1991 to 2001, 13,943 men younger than 60 years old participated in a CaP screening study. Men aged 40 to 49 years were eligible for the study if they had a positive family history or African-American heritage, and men older than 50 years were screened without respect to risk factors. The CaP detection rate, PSA velocity, pathologic features, …

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PSA Testing Recomendations

PSA Screening / By / / 1 minute of reading

The PSA test is the best way to detect prostate cancer at an early stage when there are more treatment options and the chance of survival is the highest. Read the Canadian Cancer Society’s recommendations here. This is an update from previous positions.  It was possibly brought about by the merger with Prostate Cancer Canada.

The Swinging Pendulum of PSA Screening

PSA Screening, Diagnosis / By / / 1 minute of reading

Tide of opinion turning again In 2012, the U.S. Preventive Services Task Force (USPSTF) — a powerful, voluntary group that sets guidelines for primary care physicians — came out against the mass screening of healthy men with prostate-specific antigen (PSA) blood tests for the early detection of prostate cancer. That statement, which was somewhat reversed in 2018, has lived on and continues to fuel hot debates over the use of screening and whether the guidelines themselves caused more harm than benefit. And there likely will be more arguments in the years ahead as medical groups conduct uptakes on guidelines and …

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A Re-think About PSA Testing

PSA Screening, Diagnosis / By / / 1 minute of reading

Benefits of PSA Test for Prostate Cancer Substantially Greater than Generally Appreciated The benefits of the prostate-specific antigen (PSA) test to screen men for prostate cancer may be greater than the harm, say investigators at Weill Cornell Medicine, NewYork-Presbyterian, University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center. While organizations such as the U.S. Preventative Services Task Force (USPSTF) and the American Academy of Family Physicians have been lukewarm or opposed to the routine use of the PSA test, in a commentary published in the New England Journal of Medicine, the investigators demonstrate that these recommendations …

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New test may help detect prostate cancer earlier and with greater accuracy

PSA Screening, Diagnosis / By / / 1 minute of reading

A new type of test that uses complex sugars to detect prostate cancer earlier and with greater accuracy is being developed by researchers at the University of Birmingham. The test works by identifying sugars, known as glycans, in blood. These sugars are attached to protein molecules called PSA and are known to undergo distinct but subtle changes when cancer is present in the body. Read the article.

Gleason 6 Is Bogus Prostate Cancer

PSA Screening, Active Surveillance / By / / 1 minute of reading

Noted urologic surgeon Bert Vorstman, MD, MS, FAAP, FRACS, FACS today has issued a stinging report regarding the unreliable PSA test, the mislabeling of the common Gleason 6 prostate disease as a cancer, and the misrepresentation that the radical (robotic) prostatectomy treatment is scientifically proven to be safe and effective – a charade that represents an outrageous and shameful trifecta of abominations. Read the article.

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