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New Prostate Cancer Grading System Found Superior to Gleason System

A recent study out of Johns Hopkins shows that a new and simple grading system may be effective for predicting outcomes in men with prostate cancer. In fact, the researchers say the test — in an analysis of 20,000 men — appears to be an improvement over the Gleason grading system, the current standard. Read the article.

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Alcohol, especially liquor, increases prostate risk and skews PSA

A 2013 study published in the International Journal of Cancer raises concerns about alcohol’s ability to throw off prostate cancer tests. The investigators found a modestly higher risk of prostate cancer among heavy drinkers; they also observed evidence of lower PSA levels associated with increasing consumption of alcohol. This means it can be more difficult to detect prostate cancer using PSA levels among men who are heavy drinkers. In an older study of Harvard alumni, researchers concluded wine or beer consumption was unassociated with prostate cancer; however, moderate liquor consumption was associated with a significant 61-67 percent increased risk of

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Radical Prostatectomy Versus Radiation and Androgen Deprivation Therapy for Clinically Localized Prostate Cancer: How Good Is the Evidence?

The optimal treatment of clinically localized prostate cancer is controversial. Most studies focus on biochemical (PSA) failure when comparing radical prostatectomy (RP) with radiation therapy (RT), but this endpoint has not been validated as predictive of overall survival (OS) or cause-specific survival (CSS) The available literature was analyzed to determine whether reliable conclusions could be made concerning the effectiveness of RP compared with RT with or without androgen deprivation therapy (ADT). Reliable evidence that RP provides a superior CSS to RT with ADT is lacking. The most reliable studies suggest that the differences in 10-year CSS between RP and RT

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New Cancer treatment promises to ‘obliterate’ tumours

The treatment uses a virus hidden in immune cells that seek and destroy cancer cells from within. Trials on rodents have cured cancerous growths and were alive and cancer free at the end of the 40 day study. Fifteeen British men are to start a clinical trial using the technique – the first time it has been tested in humans. Read the article.

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