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New prostate cancer test could change treatment.

Diagnosis / By / / 1 minute of reading

Schulich School of Medicine & Dentistry professor Hon Leong has developed a new blood test which could detect the potential for prostate cancer earlier. Thousands of men face a prostate biopsy following higher-than-normal results from their annual prostate-specific antigen (PSA) test, the traditional screening for prostate cancer. But recent studies have shown three in four of these biopsies were unnecessary, leading to 165,000 unnecessary procedures and 6,930 related hospitalizations each year. Read more at: http://medicalxpress.com/news/2013-02-prostate-cancer-treatment.html#jCp

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Recent Developments in Treatments for Metastatic Castration-resistant Prostate Cancer—A Mechanistic Perspective

Advanced Prostate Cancer / By / / 1 minute of reading

Abstract Over the past decade, the treatment landscape in metastatic castration-resistant prostate cancer (CRPC) has markedly changed, with the introduction of three new chemotherapeutic agents. The mechanism of CRPC is not fully understood, but it may result from multiple pathways, including a loss or androgen receptor (AR) specificity and increased downstream signalling activity that provide multiple targets for therapeutic agents. For some years, docetaxel was the mainstay of treatment in CRPC, but recently, cabazitaxel (a microtubule inhibitor), sipuleucel-T (a cancer vaccine), and abiraterone acetate (a CYP17 inhibitor) were approved for CRPC treatment. In Phase III clinical trials, these agents have

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Emotional Stress Reduces Effectiveness of Prostate Cancer Therapies in Animal Model

Psychology / By / / 1 minute of reading

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients. A new study by researchers at Wake Forest Baptist Medical Center indicates that stress is not just an emotional side effect of the diagnosis; it also can reduce the effectiveness of prostate cancer drugs and accelerate the development of prostate cancer. Read the article.

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PSA Levels Higher in Sedentary Men

Diagnosis, Exercise / By / / 1 minute of reading

PSA concentrations are higher in men who engage in more sedentary behavior and lower levels of light physical activity, a study found. It is hypothesized that regular participation in physical activity may reduce prostate cancer risk through a variety of biological mechanisms including changes in energy balance, immune function, inflammation, antioxidant defenses, and endogenous hormones. Based on their results, the authors stated, evaluation of a patient’s physical activity and sedentary level before PSA testing also is important because these factors also may influence measurements and lead to a urologic diagnostic workup. Read the whole article.

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Artificial Urinary Sphincter Implantation for Post-RP Urinary Incontinence

Incontinence / By / / 1 minute of reading

Most men with incontinence following RP have normal bladder function; their incontinence is usually due to intrinsic sphincteric urethral deficiency. When urodynamic study confirms this diagnosis and flexible cystoscopy, shows no significant urethral stricture, artificial urinary sphincter implantation is indicated. Read the Article.

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VIDEO: Dr. Padrick Warde, “Radiation Therapy for Prostate Cancer in 2012 and beyond.”

Videos, Awareness Nights, Radiation / By / / 1 minute of reading

November 2012 Awareness Night “Radiation Therapy for Prostate Cancer in 2012 and beyond.” Dr. Padrick Warde, MD, MCChB BAO, FRCPC Professor, Department of Radiation Oncology, University of Toronto Staff Radiation Oncologist, The Princess Margaret Cancer Centre/University Health Network Associate Director, Radiation Medicine Program, The Princess Margaret Cancer Centre CLICK ON THE ARROW TO START THE VIDEO Complete Presentation “Radiation Therapy for Prostate Cancer in 2012 and beyond.” High Definition 49inutes Click here to return to top. Click here to return to our main “Videos” page.

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MR-US Fusion Targeted Biopsy Boosts Detection of Prostate Cancer

Diagnosis / By / / 1 minute of reading

Targeted biopsy of suspected prostate cancer (PCa) lesions, identified using magnetic resonance-ultrasound (MR-US) fusion, increases PCa detection and detects aggressive tumors that may be missed by conventional biopsy, according to a study published in The Journal of Urology (2012;189:86-92). Read the Article.

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Newsletter December 2012

Newsletters / By / / 1 minute of reading

Awareness: The PCCN-Toronto and Side by Side Prostate Cancer Support Groups Newsletter December 2012  In this Issue: Regina  Oozes  with  Western  Hospitality at  PCCN’s  Leadership Conference with delegates appreciations  Dr.  Padraig  Warde:  The  Radiation  Story:   today  & tomorrow Dr.  Patrick  Lee:  Using  Viruses  for Prostate  Cancer  Research The 2013 Scotiabank Awareness Night Schedule Meet Fred Cohen Holiday Wishes Read it by clicking the link below to open the pdf file: December_Newsletter_2012

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List of Treatments

A List of Treatments / By / / 3 minutes of reading

Below is a partial list of possible treatments for prostate cancer. Not all of them are covered by provincial health insurance, or are even available in Canada. Some of them are only available as clinical trials, here or abroad. Discuss with your doctor which treatments may be appropriate for you. The earlier prostate cancer is detected, the more possible treatments are available to you (and the more complex your treatment decision becomes). Articles on some of these treatments can be found under Treatments in the light blue toolbar above. Primary Treatments: These are possible first treatments: – Active surveillance (A

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