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MRI-Ultrasound Fusion Biopsy Detects High-Grade Prostate Cancer

MRF-TB (magnetic resonance imaging-ultrasound fusion targeted prostate biopsy) may improve the detection of prostate cancer in men presenting for prostate biopsy. In men presenting for primary prostate biopsy MRF-TB detects more high grade cancers than systematic biopsy. Most cancers detected by systematic biopsy and not by MRF-TB are at clinically low risk. Prebiopsy magnetic resonance imaging followed by MRF-TB decreases the detection of low risk cancers while significantly improving the detection and risk stratification of high grade disease. Read the article.

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Prostate cancer patients zapped with electricity in new treatment

Traditional methods of treating prostate cancer, which attack the whole prostate with radiation or surgery, often come at the cost of the patient’s continence or erectile function. A new, less-invasive technology for getting rid of prostate cancer, known as the “nanoknife”, targets only the site of the cancer, destroying the cells of the cancer without the structures surrounding it, including the erectile and urethral nerves. In a study of 25 patients, in 76 per cent of cases the cancer had not returned after eight months. None of them developed incontinence or impotence. Read the article.

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Semen-based test for diagnosing prostate cancer could reduce unnecessary biopsies

Dr. Eleftherios Diamandis, a researcher at Toronto’s Mount Sinai Hospital, would like a better alternative that could reduce unnecessary biopsies. Dr. Diamandis plans to spend the next two years developing a non-invasive test that can help determine when high PSA levels warrant concern. To do this, he will zero in on genetic mutations found in the semen of men with prostate cancer and use those biomarkers to screen other men for the disease. Read the article.

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New test for prostate cancer significantly improves prostate cancer screening

A study from Karolinska Institutet in Sweden shows that a new test for prostate cancer is better at detecting aggressive cancer than PSA. The new test, which has undergone trial in 58,818 men, discovers aggressive cancer earlier and reduces the number of false positive tests and unnecessary biopsies. Read the article.

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Prostate Cancer Treatment Inconsistencies Found In Canada

The Canadian Partnership Against Cancer said data suggests three-quarters of men with low-risk prostate cancer in Manitoba and Prince Edward Island opted for active surveillance. In contrast, more than half of low-risk prostate cancer patients in British Columbia, Alberta, Saskatchewan and Nova Scotia were treated with surgery, radiation, or a combination, treatments with possible side-effects that include erectile dysfunction and incontinence. Read the article.

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Prostate cancer plummets: Incidence and mortality rates in free fall

The American age-adjusted incidence rate for prostate cancer peaked in 1992 at 237.4 per 100,000 men with the advent of widespread PSA screening and has been falling fast ever since. The age-adjusted mortality rate for prostate cancer peaked in 1993 — just a year after the incidence rate did — at 39.3 per 100,000 men. Explanations for the decline in the mortality rate range from improvements in treatment to American men having healthier diets. Advocates of screening say early detection has also had a hand in bending the mortality-rate curve. Read the article.

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Video: Dr. Shabbir Alibhai, “Understanding, preventing and managing side effects of hormone therapy.”

January 2016 Awareness Night   Understanding, preventing and managing side effects of hormone therapy. Dr. Shabbir Alibhai,MSc, MD, FRCPC,Princess Margaret Cancer Centre Senior Scientist, Toronto General Research Institute (TGRI) Scientist, Toronto Rehabilitation Institute (TRI) Asst Prof, Depts of Medicine and Health Policy, Management, and Evaluation at the U of Toronto CLICK ON THE ARROW TO START THE VIDEO The Complete Presentation 43:32 minutes

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African American men with prostate cancer have significantly lower PSA density than Caucasian men

A new study published in The Journal of Urology® revealed that African American men with Gleason score 3+3=6 prostate cancer (PCa) produce less prostate specific antigen (PSA) and have significantly lower PSA density (PSAD) than Caucasian men. These findings could have important implications when selecting patients for inclusion in active PCa surveillance programs. Read the article.

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Prostate Cancer: Driving the Personalized Medicine Highway

Howard Wolinsky a journalist based in the Chicago area, was diagnosed with early prostate cancer in 2010. In part one of a series he described his diagnosis and his decision to chose active surveillance. In the second part, he shared his experience during 5 years of active surveillance and in this part he tells his continuing quest to make the best — and most informed — decision about his care. Howard Wolinsky decides it may all be in the genes. Read the article.

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Australia PSA Testing Guideline Recommendations

In partnership with Cancer Council Australia and a multi-disciplinary expert advisory panel comprising urologists, medical oncologists, radiation oncologists, pathologists, general practitioners, epidemiologists, allied health professionals and consumers, Prostate Cancer Foundation of Australia has developed national evidence-based clinical practice guidelines on PSA testing and early management of test-detected prostate cancer. Read the article.

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