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Comparative Effectiveness of Targeted Prostate Biopsy Using MRI-US Fusion Software and Visual Targeting

A study compared diagnostic outcomes between 2 different techniques for targeting regions-of-interest on prostate multiparametric Magnetic resonance imaging (mpMRI); MRI-ultrasound fusion (MR-F) and visually targeted (VT) biopsy. No evidence was found of a significant difference in the detection of high-grade or any-grade cancer between VT and MR-F biopsy. However, the performance of each technique varied in specific biopsy locations, and the outcomes of both techniques were complementary. Combining VT biopsy and MR-F biopsy may optimize prostate cancer detection. Read the article.

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Prostate Ca: Site of metastases impacts prognosis

In a study of 8,820 men with metastatic castration-resistant prostate cancer, researchers found the prognosis differs substantially based on where the cancer has spread. Spread to the liver is associated with shorter survival than lung and bone spread, and patients with lymph node metastases only have the best overall survival. Read the article.

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Scientists have identified the molecules most capable of fighting prostate cancer

Scientists have identified 11 compounds that have the potential to significantly improve the diagnosis and treatment of prostate cancer, and say they could be used to develop more targeted and effective drugs so even better treatments can be offered in the future. Right now, prostate cancer – like most other forms of the disease – is fought with drugs that damage healthy cells as well as cancerous ones. Read the article.

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The 2016 Memorial Sloan Kettering Cancer Center Recommendations for Prostate Cancer Screening

The new Memorial Sloan Kettering Cancer Center’s recommendations for prostate cancer screening provide a model for prostate cancer screening that maximizes the benefits, in terms of reduction in prostate cancer-specific mortality, and minimizes harms to men from overdiagnosis and overtreatment. Read the article.

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Aggressive Prostate Cancer Appears to be Linked to Self-Renewing Stem Cells Within the Prostate

University of Texas MD Anderson Cancer Center researchers have demonstrated that the prostate basal cell layer contains self-renewing adult stem cells, with a gene expression profile that overlaps that of aggressive and endocrine therapy-resistant prostate cancers. These results indicate that such cells might be the cells-of-origin in aggressive prostate cancers, and offer a new option for anticancer therapies. Read the article.

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Aggressive Prostate Cancers Appear to Be Linked to Self-Renewing Stem Cells

University of Texas MD Anderson Cancer Center researchers have demonstrated that the prostate basal cell layer contains self-renewing adult stem cells, with a gene expression profile that overlaps that of aggressive and endocrine therapy-resistant prostate cancers. These results indicate that such cells might be the cells-of-origin in aggressive prostate cancers, and offer a new option for anticancer therapies. Read the article.

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Video: Justin Lorentz and Dr. Danny Vesprini, “Genetically Predisposed: Who is at Increased Risk of Developing Prostate Cancer?”

March 2016 Awareness Night Genetically Predisposed: Who is at Increased Risk of Developing Prostate Cancer? Justin Lorentz,  MSc, CGC Certified Genetic Counsellor, Male Oncology Research and Education (MORE) Lead, Dept of Radiation Oncology Sunnybrook Odette Cancer Centre   Dr. Danny Vesprini, MD, MSc, FRCPC Assistant Professor, U. of Toronto Dept of Radiation Oncology Affiliate Scientist, Biological Sciences, Sunnybrook Research Institute, Sunnybrook Odette Cancer Centre     CLICK ON THE ARROW TO START THE VIDEO The Complete Presentation 85:01 minutes

Video: Justin Lorentz and Dr. Danny Vesprini, “Genetically Predisposed: Who is at Increased Risk of Developing Prostate Cancer?” Read More »

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