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Comparative Effectiveness of Targeted Prostate Biopsy Using MRI-US Fusion Software and Visual Targeting

A study compared diagnostic outcomes between 2 different techniques for targeting regions-of-interest on prostate multiparametric Magnetic resonance imaging (mpMRI); MRI-ultrasound fusion (MR-F) and visually targeted (VT) biopsy. No evidence was found of a significant difference in the detection of high-grade or any-grade cancer between VT and MR-F biopsy. However, the performance of each technique varied in specific biopsy locations, and the outcomes of both techniques were complementary. Combining VT biopsy and MR-F biopsy may optimize prostate cancer detection. Read the article.

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Prostate Ca: Site of metastases impacts prognosis

In a study of 8,820 men with metastatic castration-resistant prostate cancer, researchers found the prognosis differs substantially based on where the cancer has spread. Spread to the liver is associated with shorter survival than lung and bone spread, and patients with lymph node metastases only have the best overall survival. Read the article.

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The 2016 Memorial Sloan Kettering Cancer Center Recommendations for Prostate Cancer Screening

The new Memorial Sloan Kettering Cancer Center’s recommendations for prostate cancer screening provide a model for prostate cancer screening that maximizes the benefits, in terms of reduction in prostate cancer-specific mortality, and minimizes harms to men from overdiagnosis and overtreatment. Read the article.

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New imaging test detects prostate cancer much better than any other tests in use today

Researchers at Thomas Jefferson University have found the method they developed to image the prostate appears to be much better at detecting prostate cancer than any other test — radiographical, biopsy or blood — in use today. Read the article.

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New Prostate Cancer Grading System Found Superior to Gleason System

A recent study out of Johns Hopkins shows that a new and simple grading system may be effective for predicting outcomes in men with prostate cancer. In fact, the researchers say the test — in an analysis of 20,000 men — appears to be an improvement over the Gleason grading system, the current standard. Read the article.

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MRI-Ultrasound Fusion Biopsy Detects High-Grade Prostate Cancer

MRF-TB (magnetic resonance imaging-ultrasound fusion targeted prostate biopsy) may improve the detection of prostate cancer in men presenting for prostate biopsy. In men presenting for primary prostate biopsy MRF-TB detects more high grade cancers than systematic biopsy. Most cancers detected by systematic biopsy and not by MRF-TB are at clinically low risk. Prebiopsy magnetic resonance imaging followed by MRF-TB decreases the detection of low risk cancers while significantly improving the detection and risk stratification of high grade disease. Read the article.

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Semen-based test for diagnosing prostate cancer could reduce unnecessary biopsies

Dr. Eleftherios Diamandis, a researcher at Toronto’s Mount Sinai Hospital, would like a better alternative that could reduce unnecessary biopsies. Dr. Diamandis plans to spend the next two years developing a non-invasive test that can help determine when high PSA levels warrant concern. To do this, he will zero in on genetic mutations found in the semen of men with prostate cancer and use those biomarkers to screen other men for the disease. Read the article.

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