A new analysis has found that men diagnosed with nonmetastatic prostate cancer who consumed more than 140 μg a day of supplemental selenium had over a two-and-a-half–fold excess risk for death from prostate cancer compared with nonsupplement users.

On the other hand, there was a modest 12% inverse association between selenium supplementation and the risk for overall mortality (HR, 0.88) among men who took 140 μg of a selenium supplement or more per day compared with those who didn’t use supplements.

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