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Predicting if your surgery for prostate cancer will fail

Many men who are told their surgery for prostate cancer has been a success later discover that this is not the case. The level of a protein in their blood, called prostate specific antigen, PSA, begins to rise signalling they still have prostate cells in their body even though they were told the entire prostate had been removed. There has been long standing debate about how best to predict who will fail after surgery. The current debate focuses on the value of pathologists examining the excised prostate and trying to detect, under the microscope, whether tumour cells have invaded the

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Video: A Surgeon and His Patient

September 2016 Awareness Night A Surgeon and His Patient – A Patient and His Surgeon Mark Cullen, Gardening Expert Radio and Television Personality and Best-selling Author Well-known newspaper and magazine columnist Member of the Order of Canada Prostate Cancer Survivor DR. GROLL’S PATIENT   Dr. Ryan Groll, MD, MSc, FRCPC Endourologist, Laparoscopic and Robotic Surgeon Michael Garron Hospital (Toronto East Health Network) (formerly Toronto East York General Hospital) Lectuter, Dept. of Surgery, U. of Toronto MARK CULLEN’S SURGEON   CLICK ON THE ARROW TO START THE VIDEO The Complete Presentation 52:22 minutes

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10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

This New England Journal of Medicine article gives  the results of a randomized trial of 3 possible prostate cancer treatments.  It is rather long and academic, but shows similar results for the 3 options. Read the article here.

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Extended lymph node dissection in robotic radical prostatectomy

Studies have shown that radical prostatectomy can improve progression-free and overall survival in patients with lymph node-positive prostate cancer. While this finding requires further validation, it does allow urologists to question the former treatment paradigm of aborting surgery when lymph node invasion from prostate cancer occurred, especially in patients with limited lymph node tumor infiltration. Studies show that intermediate- and high-risk patients should undergo extended pelvic lymph node dissection up to the common iliac arteries in order to improve nodal staging. Read the article.

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Erectile Function Recovery after Radical Prostatectomy in Men with High-Risk Features

The loss of erectile function after surgery Radical Prostatectomy is most frequently caused by intraoperative injury to the neurovascular bundles. It is known that if both bundles are removed, patients seldom recover erectile function. Accordingly, neurovascular bundle preservation during Radical prostatectomy has proven benefits in terms of erectile function recovery. Read the article.

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Pioneering Oxford surgery technique could improve treatment for prostate cancer

Technology developed in Oxford to make tumour cells fluorescent could improve surgery outcomes for men with prostate cancer. Fluorescent compounds show up diseased cells during keyhole operations, allowing surgeons to be more precise when removing the prostate and tissue around it. Read the article.

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Radical Prostatectomy Versus Radiation and Androgen Deprivation Therapy for Clinically Localized Prostate Cancer: How Good Is the Evidence?

The optimal treatment of clinically localized prostate cancer is controversial. Most studies focus on biochemical (PSA) failure when comparing radical prostatectomy (RP) with radiation therapy (RT), but this endpoint has not been validated as predictive of overall survival (OS) or cause-specific survival (CSS) The available literature was analyzed to determine whether reliable conclusions could be made concerning the effectiveness of RP compared with RT with or without androgen deprivation therapy (ADT). Reliable evidence that RP provides a superior CSS to RT with ADT is lacking. The most reliable studies suggest that the differences in 10-year CSS between RP and RT

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Prostate Surgery Complications: What Patients Should Know

Surgery is an effective prostate cancer treatment, but patients are understandably concerned about complications. Most men eventually recover urinary and sexual function, although many factors affect this outcome. Surgery for patients who have undergone unsuccessful radiation therapy carries a higher risk of complications. Every patient should talk with his surgeon about his own individual risk. Read the article.

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